Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Protein-surface interactions: an energy-based mathematical model.

C Ruggiero1, M Mantelli, A Curtis

  • 1DIST Department of Communication, Computer and System Science University of Genova, via Opera Pia 13, 16145 Genova, Italy. carmel@dist.unige.it

Cell Biochemistry and Biophysics
|October 26, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Response to letter to the editor, regarding "Falls prevention in community-dwelling older adults and implementation of world falls guidelines: a call for action across Europe".

European geriatric medicine·2025
Same author

Acute and chronic systemic inflammation associated with canine nodular splenic lesions composed of heterogeneous cell components: four cases (2020-2024).

The Journal of small animal practice·2025
Same author

Dementia, osteoporosis and fragility fractures: Intricate epidemiological relationships, plausible biological connections, and twisted clinical practices.

Ageing research reviews·2023
Same author

Anti-resorptive therapy in the osteometabolic patient affected by periodontitis. A joint position paper of the Italian Society of Orthopaedics and Traumatology (SIOT) and the Italian Society of Periodontology and Implantology (SIdP).

Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology·2023
Same author

Optical interferometry-based array of seafloor environmental sensors using a transoceanic submarine cable.

Science (New York, N.Y.)·2022
Same author

Real-time monitoring of volume flow, mass flow and shredder power consumption in mixed solid waste processing.

Waste management (New York, N.Y.)·2021
Same journal

From Isoprene Units to Polyprenols and Dolichols: 70 Years of Polyisoprenoid Biosynthesis Research.

Cell biochemistry and biophysics·2026
Same journal

Therapeutic Insights into the Hepatoprotective Effect of Strobilanthes callosa.

Cell biochemistry and biophysics·2026
Same journal

The Dual Role of TGF-β and Hypoxia on MMP14-Mediated Invasion in PC3 Cells.

Cell biochemistry and biophysics·2026
Same journal

Microalgae-Mediated Synthesis of Gold Nanoparticles from Indonesian Chlorella vulgaris InaCC M205 with Potential Anticancer Properties for Biomedical Application.

Cell biochemistry and biophysics·2026
Same journal

Adsorption-driven Graphene Oxide SPR Biointerfaces: Coupled Thermodynamic, Kinetic, and Optical Modeling with Effective-layer Validation.

Cell biochemistry and biophysics·2026
Same journal

Identification of Ferroptosis-related Genes Associated with the Prognosis of Hepatocellular Carcinoma.

Cell biochemistry and biophysics·2026
See all related articles

This study introduces an energy-based model for protein adsorption, revealing that hydrophobic/hydrophilic interactions significantly influence protein binding to surfaces, crucial for designing biocompatible materials.

Area of Science:

  • Biomaterials Science
  • Surface Chemistry
  • Physical Chemistry

Background:

  • Protein adsorption on surfaces is critical for biomaterial performance and biocompatibility.
  • Understanding the forces governing protein-surface interactions is essential for material design.
  • Existing models often focus on van der Waals and electrostatic forces, potentially overlooking other key factors.

Purpose of the Study:

  • To develop and apply an energy-based approach to model protein adsorption.
  • To investigate the relative contributions of different energies (van der Waals, electrostatic, hydrophobic/hydrophilic) to protein adsorption.
  • To explore the impact of fluid motion on protein adsorption dynamics.

Main Methods:

  • Utilized mathematical modeling and simulation techniques.

Related Experiment Videos

  • Incorporated van der Waals, electrostatic, and hydrophobic/hydrophilic energies into the model.
  • Included kinetic energy contributions from fluid motion and drag effects.

    • Main Results:

    • Protein adsorption is significantly influenced by hydrophobic/hydrophilic interactions, not solely by van der Waals and electrostatic energies.
    • Fluid motion and its associated kinetic energy play a role in adsorption behavior.
    • The model provides a more comprehensive understanding of protein-surface interactions.

    Conclusions:

    • Hydrophobic/hydrophilic interactions are key determinants of protein adsorption behavior.
    • The developed energy-based model enhances understanding for designing biocompatible materials.
    • Findings align with and support existing experimental observations in protein adsorption studies.