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Direct FTIR assay of streptomycin in agar
Richard J L Meanwell1, Gilbert Shama
1Department of Chemical Engineering, Loughborough University, LE11 3TU, Loughborough, Leicestershire, UK.
Biotechnology Letters
|October 26, 2005
Abstract:
Streptomycin titres in samples of agar media on which various species of streptomycetes were cultured were obtained by Fourier Transform Infra Red (FTIR) spectroscopy. Titres were directly comparable to those obtained by bioassay based on Bacillus subtilis inhibition. Analysis by this method could be used to facilitate the isolation of high level antibiotic-producing mutants.
