[Malassezia fungal blepharitis: a case report]

Area of Science:

• Ophthalmology
• Mycology

Background:

• Blepharitis is a common eyelid disorder with a debated role for fungal infections.
• Investigating the etiopathogenesis of chronic blepharitis is crucial for effective treatment.

Observation:

• A case study of a 29-year-old man with severe, recurrent blepharitis unresponsive to conventional treatments.
• Clinical examination revealed seborrhea and a sticky substance at the eyelash roots, progressing to microulcerations.
• Fungal examination identified Malassezia furfur, a yeast implicated in skin conditions.

Findings:

• Standard blepharitis treatments (antibiotics, steroids) provided only temporary relief.
• Topical ketoconazole, an antifungal agent, completely resolved the blepharitis symptoms.
• The patient remained symptom-free for 5 months post-treatment.

Implications:

• Malassezia furfur can be a causative agent in chronic blepharitis, potentially due to hypersensitivity or overgrowth.
• Antifungal treatment, specifically targeting Malassezia, should be considered for recalcitrant blepharitis cases.
• Routine fungal screening is recommended for patients with recurrent or persistent blepharitis.