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Aortic lysosomal hydrolases and pathological alterations in hypertensive and/or atherogenic diet fed rhesus monkeys

G S Dhaunsi1, S Majumdar, R N Chakravarti

  • 1Department of Experimental Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Journal of Experimental Pathology
|January 1, 1992
PubMed

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Lysosomal Hydrolases01:22

Lysosomal Hydrolases

Lysosomes are the site for the degradation of macromolecules and biological polymers released during membrane trafficking events such as secretory, endocytic, autophagic, and phagocytic pathways. The membrane-enclosed area of the lysosome, called the lumen, contains hydrolytic enzymes active in an acidic environment. These acid hydrolases are functional at a pH between 4.5 and 5 and are involved in cellular processes such as cell signaling, energy metabolism, restoration of the plasma membrane,...