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Post-vagotomy variations of gastric mucosal mast cells in the rat
J L Marcos Rodríguez1, J M Alcalde Escribano, A Brea Hernando
1Department of Pathology, Faculty of Medicine, University of Cantabria, Santander, Spain.
Abstract:
The effects of the vagus and its action on the mucosal mast cells (MMC) of the secretory portion of the rat stomach are analyzed by observing the consequences caused by subdiaphragmatic truncal vagotomy on the MMC in terms of cell count and degranulation over a period of four months. Observations showed a gradual decrease in the number of mast cells/mm2, an increase in the percentage of MMC in a state of degranulation, but the same number of degranulated cells/mm2. This suggests that the vagus controls both numerically and functionally the MMC population in the secretory portion of the rat stomach.