Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Synthetic biology.

A Michael Sismour, Steven A Benner

    Expert Opinion on Biological Therapy
    |November 1, 2005
    PubMed
    Summary
    This summary is machine-generated.

    Synthetic biology leverages chemical synthesis to create novel biological systems, driving discovery beyond traditional analysis. This approach advances our understanding of genetics and yields practical applications in healthcare.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Recognition of non-standard base pairs by triplex-forming oligonucleotides containing an expanded genetic alphabet.

    Nature communications·2026
    Same author

    Ribose Accumulation in Borate-Rich Prebiotic Environments.

    Astrobiology·2026
    Same author

    Viking Mars, Now 50 Years Old, Still Needs a Scientific Analysis.

    Astrobiology·2025
    Same author

    Interstep compatibility of a model for the prebiotic synthesis of RNA consistent with Hadean natural history.

    Proceedings of the National Academy of Sciences of the United States of America·2025
    Same author

    Draft genome and alcohol dehydrogenase dataset of thermoanaerobacter uzonensis bacterium strain AK85.

    Data in brief·2025
    Same author

    Improving the Fidelity of Replication of a Six-Letter DNA Alphabet.

    ACS chemical biology·2025
    Same journal

    TNF inhibitors for the long-term management of juvenile idiopathic arthritis associated uveitis: real-life data from the ITHACA cohort.

    Expert opinion on biological therapy·2026
    Same journal

    Type 2 inflammation and biologics: a twenty-year journey.

    Expert opinion on biological therapy·2026
    Same journal

    Current outlook on the use of biological agents to improve outcomes in adult secondary hemophagocytic lymphohistiocytosis.

    Expert opinion on biological therapy·2026
    Same journal

    Addressing challenges in disease management of childhood-onset systemic lupus erythematosus: the role of biologics, with primary focus on rituximab and belimumab.

    Expert opinion on biological therapy·2026
    Same journal

    Biological drugs for the treatment of children with atopic dermatitis.

    Expert opinion on biological therapy·2026
    Same journal

    Optimizing biologic therapy in psoriasis: dose adjustment, treatment duration, and tapering-an expert perspective.

    Expert opinion on biological therapy·2026
    See all related articles

    Area of Science:

    • Synthetic biology
    • Chemical synthesis
    • Molecular biology
    • Genetics

    Background:

    • Chemistry's power lies in synthesizing new matter, enabling the testing of structure-behavior models independent of natural constraints.
    • The application of synthesis to living systems began in the 1980s with recombinant DNA technology and automated DNA synthesis.
    • This integration revealed that synthesis, not just analysis, is a primary driver of biological discovery and understanding.

    Discussion:

    • Synthetic biology aims to replicate emergent properties of natural biological systems in artificial constructs.
    • This endeavor deepens the understanding of the molecular underpinnings of genetics, surpassing the limitations of analytical methods alone.
    • The field has already produced artificial genetic systems benefiting approximately 400,000 Americans annually through improved healthcare.

    Related Experiment Videos

    Key Insights:

    • Synthesis is a fundamental driver of discovery in biology, mirroring its role in chemistry.
    • Artificial genetic systems offer tangible benefits in healthcare.
    • Direct construction of artificial Darwinian systems represents the next frontier in synthetic biology.

    Outlook:

    • The development of artificial Darwinian systems through direct construction is the next major goal.
    • This research, supported by the National Science Foundation's Chemical Bonding program, promises to elucidate the fundamental workings of biological systems.
    • Continued advancements in synthetic biology are expected to yield further innovations in medicine and our comprehension of life's molecular basis.