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Effect of systemic hormonal cyclicity on skin.
Neelam Muizzuddin1, Kenneth D Marenus, Steven F Schnittger
1Estee Lauder Companies, 125 Pinelawn Road, Melville, NY 11747.
Journal of Cosmetic Science
|November 1, 2005
Summary
Menstrual cycle phases impact skin properties. Skin barrier weakens and UV-B susceptibility increases in the late cycle, while dryness peaks early and lipid secretion is highest mid-cycle.
Area of Science:
- Dermatology
- Gynecology
- Endocrinology
Background:
- Hormonal fluctuations during the menstrual cycle influence various bodily systems.
- Understanding these effects on skin health is crucial for targeted skincare and dermatological treatments.
Purpose of the Study:
- To investigate the correlation between specific menstrual cycle phases and changes in skin properties.
- To assess variations in skin barrier function, hydration, lipid secretion, microflora, and UV-B sensitivity.
Main Methods:
- Weekly measurements of skin barrier strength, dryness, lactic acid stinging response, surface lipids, and microflora.
- Assessment of Ultraviolet B (UV-B) susceptibility using minimal erythemal dose (MED).
- Studies conducted over 2-3 months on healthy Caucasian women with regular menstrual cycles.
Main Results:
- Skin barrier strength was lowest between days 22-26.
- Skin dryness was most pronounced during days 1-6.
- Skin surface lipid secretion peaked around days 16-20.
- Highest microbial counts were observed between days 16-22.
- Increased UV-B susceptibility was noted between days 20-28.
- Neuronal response to lactic acid did not significantly vary with the cycle.
Conclusions:
- Menstrual cycle phases significantly influence skin properties, including barrier function, hydration, lipid production, and UV-B sensitivity.
- These cyclical skin changes suggest a need for phase-specific dermatological care and cosmetic product development.
- Further research can elucidate the precise hormonal mechanisms driving these observed skin variations.