Related Experiment Video
Updated: Jul 17, 2026
08:12
Normothermic Ex Vivo Kidney Perfusion for the Preservation of Kidney Grafts prior to Transplantation
Published on: July 15, 2015
Living-related kidney donation.
J J Wynn1, J E Barnett, L L Mulloy
1Departments of Surgery and Medicine, Medical College of Georgia, Augusta, Georgia, USA. jwynn@mail.mcg.edu
Journal of the Medical Association of Georgia
|November 2, 2005
Summary
Living donation expands organ transplant options, offering recipients greater convenience and long-term success. Careful donor screening minimizes risks, making living organ donation a vital choice for kidney, liver, and lung transplants.
Area of Science:
- Nephrology
- Hepatology
- Pulmonology
- Transplantation Medicine
Background:
- Living organ donation is crucial for increasing the availability of organs for transplantation.
- It offers recipients improved convenience and potentially better long-term outcomes.
- Established for kidney donation, its application is expanding to other organs.
Purpose of the Study:
- To evaluate the effectiveness and safety of living organ donation.
- To explore the expanding role of living donation in extra-renal transplantation.
- To assess the future importance of living donation for various organ recipients.
Main Methods:
- Review of existing literature and clinical data on living organ donation.
- Analysis of outcomes for recipients and risks for living donors.
- Assessment of current practices and future trends in living transplantation.
Main Results:
- Living renal donation significantly expands the donor pool, enabling more transplants.
- Recipient risks are minimal with rigorous donor screening protocols.
- Early experiences suggest living donation is a viable option for liver and lung transplants.
Conclusions:
- Living organ donation is an effective strategy to enhance organ availability and transplant success.
- Careful donor selection is paramount to ensuring recipient safety.
- Living donation is poised to become an increasingly important option for liver and lung recipients.
Related Concept Videos
01:45Kidney Structure
The kidneys are two large bean-shaped organs located in the upper abdomen. They filter the blood several times a day to remove toxins and rebalance water and electrolytes of the circulatory system via the renal veins. The kidneys receive blood directly from the heart via the renal arteries. These arteries enter the kidney at the hilum, the concave surface of the bean, where they branch and divide into smaller vessels and capillaries.
01:22Bone Marrow Sampling and Transplants
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
01:24Tissue Transplantation
Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
01:28Kidney Transplant I: Introduction
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
01:26Kidney Transplant II: Surgical Procedure
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
01:16Kidney Transplant III: Nursing Management
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...