Related Experiment Video
Updated: Aug 15, 2026

Non-Intubated Video-Assisted Thoracoscopic Surgery
Published on: May 26, 2023
Combined spinal-propofol anesthesia with noninvasive positive-pressure ventilation
Hiroshi Ohmizo1, Tomoko Morota, Yasuhiro Seki
1Department of Anesthesiology, Central Aizu General Hospital, Aizuwakamatsu, Japan.
Abstract:
Twenty-three adult patients undergoing repair of inguinal hernia under spinal anesthesia received propofol infusion for sedation with the assist of noninvasive positive-pressure ventilation (NPPV). Circulatory and respiratory parameters, such as percutaneous oxygen saturation, transcutaneous carbon dioxide tension, respiratory rate, tidal volume, blood pressure, and heart rate, were maintained within physiological ranges during the anesthesia. There were no adverse effects. These findings suggest that the application of NPPV in patients receiving propofol infusion for sedation is clinically practicable during anesthesia.
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