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Oral Biofilm Sampling for Microbiome Analysis in Healthy Children
Published on: December 31, 2017
Onychomycosis in children: a survey of 46 cases
C Romano1, M Papini, A Ghilardi
1Department of Dermatology, University of Siena, Italy. mondelli@unisi.it
Insights
Pediatric onychomycosis, a fungal nail infection, is often caused by dermatophytes like Trichophyton rubrum. Early diagnosis and treatment are crucial for successful recovery and preventing nail damage.
Area of Science:
- Dermatology
- Mycology
- Pediatric Infectious Diseases
Background:
- Onychomycosis, a fungal nail infection, can affect children, necessitating understanding of its causative agents and clinical presentation.
- Previous studies on pediatric onychomycosis are limited, highlighting the need for more data on epidemiology and treatment outcomes.
Purpose of the Study:
- To retrospectively analyze the causative agents, clinical features, infection sources, and therapeutic outcomes of onychomycosis in children.
- To emphasize the importance of early diagnosis and prompt treatment in managing pediatric onychomycosis.
Main Methods:
- Retrospective analysis of 46 pediatric patients diagnosed with onychomycosis between 1989 and 2000.
- Identification of fungal pathogens through mycological diagnosis, including dermatophytes, Candida species, and molds.
Main Results:
- Dermatophytes were the most common cause (30 cases), particularly Trichophyton rubrum (22 cases).
- Candida species were isolated in 16 cases, and molds in three cases.
- Distal and distolateral subungual hyperkeratosis were common in dermatophyte infections (93%), while onychodystrophy and paronychia were frequent in Candida infections (56% and 50%).
- Forty patients achieved complete clinical and mycological recovery.
Conclusions:
- Onychomycosis is a significant concern in children, with dermatophytes being the primary etiology.
- Prompt microbiological diagnosis and early intervention are essential for effective treatment and preventing long-term nail damage.
- Suspecting onychomycosis in children and initiating timely management can prevent disease progression and spread.
Abstract:
This is a retrospective study of the agents, clinical aspects, sources of infection and therapy of onychomycosis in children. In the period 1989-2000, we observed 46 consecutive children, until 16 years of age with onychomycosis (29 boys, 17 girls, mean age 10.8 years). Dermatophytes were isolated in 30 cases (Trichophyton rubrum in 22 cases, Trichophyton mentagrophytes in five, Epidermophyton floccosum in two and Trichophyton violaceum in one) and Candida spp. in 16, associated with Trichophyton rubrum in two. Moulds were isolated in three children (Fusarium oxysporum in one, Scopulariopsis brevicaulis in another and Aspergillus fumigatus associated with Trichophyton rubrum in a third). The commonest features were distal and distolateral subungual hyperkeratosis in dermatophyte infections (93%) and onychodystrophy and paronychia in Candida infections (56% and 50% respectively). Forty patients achieved clinical and mycological recovery. It is appropriate to suspect onychomycosis in children, perform microbiological diagnosis and undertake early treatment. An approach of this kind may help to prevent nail dystrophy and the spread of infection.
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