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Updated: Aug 15, 2026

Systematic Bronchoscopy: the Four Landmarks Approach
Published on: June 23, 2023
Use of continuous positive airway pressure during flexible bronchoscopy in young children
D Trachsel1, T O Erb, F J Frei
1Division of Paediatric Intensive Care and Pulmonology, University Children's Hospital of Basel, Post Office Box, 4005 Basel, Switzerland.
Insights
Continuous positive airway pressure (CPAP) significantly improves ventilation in young children undergoing flexible bronchoscopy. This intervention helps reverse decreases in tidal volume and respiratory flow, enhancing patient safety during the procedure.
Area of Science:
- Pediatric Pulmonology
- Anesthesiology
- Respiratory Physiology
Background:
- Young children face higher risks of hypoxemia and hypercapnia during flexible bronchoscopy due to airway anatomy.
- Preventive strategies are crucial to maintain adequate ventilation and oxygenation in this population.
Purpose of the Study:
- To evaluate the effect of continuous positive airway pressure (CPAP) on ventilation during flexible bronchoscopy in infants and young children.
Main Methods:
- Ultrasound spirometry measured tidal breathing in 16 spontaneously breathing, sedated children (3-25 months).
- Measurements were taken with the bronchoscope in the pharynx (no CPAP) and mid-trachea (0, 5, 10 cmH2O CPAP).
Main Results:
- Bronchoscope passage through vocal cords caused significant reductions in tidal volume and peak expiratory/inspiratory flows.
- CPAP at 5-10 cmH2O largely reversed these observed decreases in ventilation parameters.
Conclusions:
- Flexible bronchoscopy in spontaneously breathing children leads to reduced tidal volume and respiratory flow.
- CPAP is an effective method to counteract these ventilation changes, improving outcomes during the procedure.
Abstract:
Young children are at increased risk for hypoxaemia and hypercapnia during flexible bronchoscopy due to the small size and increased collapsibility of their airways. Various strategies are used to prevent hypoventilation and to provide oxygen during the procedure. The aim of this study was to assess the impact of continuous positive airway pressure (CPAP) on ventilation during flexible bronchoscopy in infants and young children. Tidal breathing was measured in 16 spontaneously breathing and deeply sedated children, aged 3-25 months, by ultrasound spirometry via an airway endoscopy mask. Measurements were made with the tip of the bronchoscope positioned in the pharynx with no CPAP, and in mid-trachea with 0, 5 and 10 cmH2O of CPAP. Transition of the bronchoscope through the vocal cords was associated with significant decreases of tidal volumes (5.0+/-0.5 versus 3.4+/-0.5 mL.kg(-1)), peak tidal expiratory flows (78+/-12 versus 52+/-10 mL.s(-1)) and peak tidal inspiratory flows (98+/-15 versus 66+/-12 mL.kg(-1)). CPAP (5-10 cmH2O) induced almost complete reversal of these changes. In conclusion, it is shown here that flexible bronchoscopy in spontaneously breathing young children is associated with significant decreases in tidal volume and respiratory flow. These changes are largely reversible with continuous positive airway pressure.
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