Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Multiple primary cutaneous plasmacytomas.

T Green1, J Grant, R Pye

  • 1Department of Dermatology, Addenbrooke's Hospital, Cambridge, England.

Archives of Dermatology
|July 1, 1992
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical and radiographic predictors for angiography in pelvic trauma: An analysis of 1703 patients.

Injury·2024
Same author

Coevolution with hosts underpins speciation in brood-parasitic cuckoos.

Science (New York, N.Y.)·2024
Same author

Dientamoeba fragilis associated with microbiome diversity changes in acute gastroenteritis patients.

Parasitology international·2023
Same author

From farm sustainability to ecosystem sustainability: Exploring the limitations of farm-applied aquaculture eco-certification schemes.

Journal of environmental management·2023
Same author

Lung lobe torsion in association with a pulmonary papillary carcinoma in a dog.

Journal of the South African Veterinary Association·2022
Same author

Micromolar Metabolite Measurement in an Electronically Multiplexed Format.

IEEE transactions on bio-medical engineering·2022
Same journal

Scoring With SCORTEN-Reply.

Archives of dermatology·2017
Same journal

Comparison of Early and Late Latent Syphilis- Colorado, 1991.

Archives of dermatology·2016
Same journal

Case of Rhinoscleroma.

Archives of dermatology·2016
Same journal

Cutaneous Fungal Infections.

Archives of dermatology·2016
Same journal

An Ulcerated Plaque in a Gay Man.

Archives of dermatology·2016
Same journal

Solitary Violaceous Nodule on the Face.

Archives of dermatology·2016
See all related articles

Primary cutaneous plasmacytoma is a rare skin tumor. This case highlights its monoclonality and successful treatment with chemotherapy and radiotherapy, with bone marrow preservation for potential future relapse.

Area of Science:

  • Oncology
  • Dermatology
  • Hematology

Background:

  • Primary cutaneous plasmacytoma is an uncommon skin tumor, often associated with advanced multiple myeloma.
  • Few cases of primary cutaneous plasmacytoma exist, with many patients progressing to systemic disease.
  • Some patients with cutaneous plasmacytoma do not develop bone marrow involvement.

Observation:

  • A patient developed multiple primary cutaneous plasmacytomas following a possible insect bite reaction.
  • Immunohistochemical techniques confirmed the monoclonality of the tumor cells.
  • The patient received chemotherapy and local radiotherapy, remaining disease-free for 3 years.

Findings:

  • This case demonstrates the monoclonality of plasma cells in cutaneous plasmacytoma using immunohistochemistry.

Related Experiment Videos

  • Unlike other extramedullary plasmacytomas, cutaneous plasmacytomas have a high early mortality rate.
  • The patient's bone marrow was cryopreserved for potential autologous bone marrow transplantation.

    • Implications:

    • This case underscores the importance of immunohistochemical confirmation of monoclonality in cutaneous plasmacytoma.
    • Aggressive treatment strategies, including combination chemotherapy and radiotherapy, may be effective.
    • Bone marrow cryopreservation is a crucial consideration for managing patients with cutaneous plasmacytoma due to the risk of systemic relapse.