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Urine sediment from a Chihuahua.
Valarie Pallatto1, Michael Wood, Carol Grindem
1Department of Population Health, North Carolina State University, College of Veterinary Medicine, Raleigh, NC, USA. valarie_pallatto@ncsu.edu
Veterinary Clinical Pathology
|November 5, 2005
Summary
A Chihuahua diagnosed with cystinuria experienced painful urination and bladder stones. The stones, composed entirely of cystine, highlighted the importance of identifying cystine crystals for diagnosing this inherited kidney condition.
Area of Science:
- Veterinary Medicine
- Canine Urology
- Medical Genetics
Background:
- Cystinuria is an inherited disorder affecting renal tubular transport of amino acids.
- It leads to the formation of cystine uroliths (stones) in the urinary tract.
- This condition can affect various dog breeds, often presenting as an autosomal recessive trait.
Observation:
- A 6-year-old intact male Chihuahua presented with stranguria and painful urination.
- Urine sediment analysis revealed a low number of cystine crystals.
- Surgical removal of uroliths from the urethra and bladder was performed.
Findings:
- Mineral analysis confirmed the uroliths were composed of 100% cystine.
- The clinical signs and diagnostic findings supported a diagnosis of cystinuria.
- The case highlights the breed-specific manifestations and diagnostic markers of canine cystinuria.
Implications:
- Accurate identification of cystine crystals in urine is crucial for diagnosing cystinuria.
- Understanding the genetic basis and clinical presentation aids in managing affected dogs.
- This case underscores the importance of urolith analysis in veterinary urology.