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Updated: Aug 15, 2026

A Volumetric Method for Quantification of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage
Published on: July 28, 2018
Volume determination of intracranial aneurysms using 16-row multislice computed tomography angiography: a systematic
Oliver Dudeck1, Krzysztof Jurczyk, German Abdo
1Department of Radiology, Charité, Campus Virchow Clinic, Berlin, Germany. oliver.dudeck@charite.de
Objective:
To assess multislice computed tomography (CT) angiography for volume determination of intracranial aneurysms.
Methods:
Submillimetric 16-row multislice CT angiography was performed with optimized scan parameters on precision spheres and a soft carotid artery model harboring 3 aneurysms connected to a pulsatile circuit. The CT angiography images were produced using optimized techniques for axial, multiplanar reformation, maximum intensity projection, surface-shaded display, and volume-rendered images. Measurements were made with electronic precision calipers by segmentation according to the method of Cavalieri and by the use of automated volumetric analysis software.
Results:
Segmentation resulted in precise and accurate volume estimates of aneurysms, but small volumes were underestimated and evaluation time was long (36:44 minutes). Automated volume evaluation from volume-rendered reconstructions also resulted in low measurement error, although the evaluation process was significantly faster (3:25 minutes; P < 0.0001).
Conclusions:
The use of an automated volume analysis tool on volume-rendered reconstructions is recommended for time-efficient volume assessment of intracranial aneurysms.
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