[Experimental study of relationships of carbotexim-M to the adjacent tissues during its subcutaneous implantation]

A Russian Carbotexim-M carbonic felt was implanted into the subcutaneous pocket on the back of albino nice. Gross and morphological analysis of changes in rejection was first performed during 4 months and the status after material yield and skin defect healing was also analyzed after 4 months. The risk factors of rejection were the excessive volume of an implant, epithelial thickness and metabolism, the abrasive effect of Carbotexim-M particles. These data indicate the potential problems associated with the superficial implantation of the material in clinical practice.