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Observational research databases in renal disease.

Michael Shlipak1, Catherine Stehman-Breen

  • 1General Internal Medicine Section, Veterans Affairs Medical Center, and Departments of Medicine, Epidemiology, and Biostatistics, University of California, San Francisco, San Francisco, California, USA.

Journal of the American Society of Nephrology : JASN
|November 11, 2005
PubMed
Summary
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This review explores using existing patient data for observational research, particularly for kidney disease studies. It details available databases and methods for answering key research questions efficiently.

Area of Science:

  • Nephrology
  • Clinical Research
  • Epidemiology

Background:

  • Observational, patient-oriented research involves studies without experiments or interventions.
  • These studies can utilize primary data collection or existing patient data.
  • Using previously collected data is cost-effective but has limitations.

Purpose of the Study:

  • To review research analyses possible with existing databases.
  • To outline available research databases for patient-oriented studies.
  • To provide an approach for using existing data to answer research questions.

Main Methods:

  • Review of existing literature on observational research.
  • Analysis of types of research databases.
  • Discussion of methodologies for using secondary data.

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Main Results:

  • Existing databases offer numerous opportunities for kidney disease research.
  • Different types of analyses can be performed on these databases.
  • A structured approach facilitates effective research question addressing.

Conclusions:

  • Existing patient databases are valuable resources for observational research.
  • Careful consideration of database limitations is crucial.
  • This approach enables efficient and cost-effective research, especially in nephrology.