Related Experiment Videos
[Diagnostic pitfall: herpes simplex recidivans on the finger]
Peter Weisenseel1, Erika Sander, Jörg Prinz
1Klinik und Poliklinik für Dermatologie und Allergologie, Ludwig-Maximilians-Universität, München. peter.weisenseel@derma.med.uni-muenchen.de
Summary
Recurrent herpes simplex virus infections can occur in unusual locations, leading to misdiagnosis. This case highlights how atypical herpes simplex virus on the finger was confirmed by PCR testing.
Area of Science:
- Dermatology
- Virology
- Infectious Diseases
Background:
- Herpes simplex virus (HSV) infections are common, typically presenting in perioral, labial, or genital areas.
- Diagnosis of typical HSV infections is often straightforward and patient-recognized.
- Atypical HSV presentations can be challenging, leading to physician misdiagnosis and delayed treatment.
Observation:
- A 28-year-old patient experienced recurrent herpes simplex virus exacerbations on his left index finger.
- Symptoms included neuralgic pain and lymphadenitis.
- The patient had a history of misdiagnosis by various specialists over several years, impacting his ability to work.
Findings:
- The patient's history and clinical presentation suggested recurrent herpes simplex virus.
- Herpes simplex virus-specific DNA was detected using Polymerase Chain Reaction (PCR).
- This confirmed the diagnosis of atypical herpes simplex virus infection.
Implications:
- Highlights the importance of considering atypical herpes simplex virus in cases of recurrent infections with unusual localization.
- Emphasizes the diagnostic value of PCR for confirming herpes simplex virus in challenging cases.
- Underscores the potential for significant patient morbidity and work disability due to misdiagnosed herpes simplex virus infections.