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[Hemiplegic migraine complicated with coronary vasospasm]
I Takeuchi1, T Hata, H Itagaki
1Department of Neurology, Tokyo Saiseikai Central Hospital.
Rinsho Shinkeigaku = Clinical Neurology
|January 1, 1992
Summary
This case study explores hemiplegic migraine and coronary vasospasm, suggesting a potential link between vascular events in the brain and heart. Further research is needed to understand this migraine pathogenesis connection.
Area of Science:
- Neurology
- Cardiology
- Vascular Medicine
Background:
- Migraine pathogenesis is debated, with vascular theories supported by drug effectiveness and cerebral blood flow studies.
- Hemiplegic migraine is a rare subtype characterized by temporary neurological deficits, often resembling stroke symptoms.
Observation:
- A 26-year-old male experienced recurrent hemiplegic migraine attacks with transient right-sided weakness and numbness.
- During a migraine attack, he also reported chest oppression, indicative of angina pectoris.
- Coronary angiography revealed vasospasm in the left anterior descending coronary artery, which resolved with nitroglycerin.
Findings:
- The patient presented with concurrent hemiplegic migraine and coronary vasospasm.
- Despite neurological symptoms, neuroimaging (MRI, CT, EEG) showed no significant abnormalities.
- Nitroglycerin resolved coronary vasospasm, but subsequent hemiplegic migraine attacks occurred.
Implications:
- This case highlights a potential association between migraine and coronary artery vasospasm.
- It suggests that shared vascular mechanisms might underlie both conditions.
- Further investigation into the vascular pathogenesis of migraine is warranted, particularly in cases with cardiac comorbidities.