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Tuberculosis peritonitis in Negara Brunei Darussalam
1Gastroenterology Unit, Department of Medicine, Raja Isteri Pengiran Anak Saleha (RIPAS) Hospital, Negara Brunei Darussalam. chongvuih@yahoo.co.uk
Annals of the Academy of Medicine, Singapore
|November 15, 2005
Summary
Tuberculosis peritonitis (TBP) is uncommon, with patients showing lower hemoglobin and albumin levels. TBP patients also experienced more adverse drug reactions compared to pulmonary tuberculosis (PTB).
Area of Science:
- Medical microbiology
- Infectious diseases
- Gastroenterology
Background:
- Tuberculosis peritonitis (TBP) is a rare form of extrapulmonary tuberculosis.
- Symptoms of TBP are often non-specific, leading to diagnostic challenges.
- Limited local data exist on the clinical characteristics and outcomes of TBP.
Purpose of the Study:
- To review the local experience with tuberculosis peritonitis.
- To describe the clinical presentation, diagnosis, and treatment outcomes of TBP.
- To compare TBP cases with pulmonary tuberculosis (PTB) patients.
Main Methods:
- Retrospective review of 10 histologically confirmed TBP cases (1996-2004).
- Comparison of TBP patients with a cohort of pulmonary tuberculosis (PTB) patients.
- Diagnostic methods included laparoscopy, laparotomy, and peritoneal biopsy.
Main Results:
- TBP prevalence was 0-1.01% of all TB infections; median symptom duration was 2 months.
- Common symptoms included abdominal distension (70%), pain (60%), fever (60%), anorexia (60%), and weight loss (40%).
- TBP patients had significantly lower hemoglobin and serum albumin levels and experienced more adverse drug events (80%) compared to PTB patients.
Conclusions:
- Tuberculosis peritonitis is uncommon in the studied population.
- Lower hemoglobin and serum albumin levels are characteristic of TBP.
- Increased adverse events during anti-TB treatment are observed in TBP patients.