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Updated: Aug 14, 2026

Investigations on Alterations of Hippocampal Circuit Function Following Mild Traumatic Brain Injury
Published on: November 19, 2012
Cognitive recovery from Encephalitis Lethargica
Bonnie-Kate Dewar1, Barbara A Wilson
1MRC Cognition and Brain Sciences Unit, Aldenbrooke's Hospital, Cambridge, UK. bonnie-kate.dewar@mrc-cbu.cam.ac.uk
Abstract:
The cognitive profile and outcome of Encephalitis Lethargica has not been systematically described in the literature. Treatment has typically focused upon medical management. The first case report of a patient with Encephalitis Lethargica who underwent a systematic programme of cognitive rehabilitation is presented. Initial neuropsychological assessment conducted during her acute presentation indicated generalized cognitive dysfunction, including memory and executive function impairments. An outpatient cognitive rehabilitation programme addressed the development of awareness and the remediation of memory and executive function impairments. Repeat assessment indicated significant improvement in cognitive function. The components of her rehabilitation programme are discussed. She has been able to successfully return to her pre-morbid level of work responsibility within 8 months of her admission.
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