Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Keratomycosis in Wisconsin.

G N Chin, R A Hyndiuk, G P Kwasny

    American Journal of Ophthalmology
    |January 1, 1975
    PubMed
    Summary

    Candida albicans caused most fungal eye infections in a northern climate. Pimaricin effectively treated these Candida infections and a resistant Aspergillus case.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Treatment of vernal keratoconjunctivitis with topical cromolyn sodium.

    Journal of pediatric ophthalmology and strabismus·2014
    Same author

    Screening for glaucoma with stereo disc photography.

    Journal of glaucoma·2009
    Same author

    Effects of external beam irradiation on the TRAM flap: an experimental model.

    Plastic and reconstructive surgery·2001
    Same author

    Accuracy of glaucoma detection with frequency-doubling perimetry.

    American journal of ophthalmology·2000
    Same author

    Accuracy of scanning laser polarimetry in the diagnosis of glaucoma.

    Archives of ophthalmology (Chicago, Ill. : 1960)·1999
    Same author

    A new technique for the treatment of flexor digitorum profundus tendon avulsion.

    Annals of plastic surgery·1999

    Area of Science:

    • Ophthalmology
    • Mycology
    • Infectious Diseases

    Background:

    • Fungal keratitis presents a significant challenge in ophthalmology.
    • Geographic variations exist in the prevalence of fungal species causing keratitis.
    • Antifungal resistance can complicate treatment outcomes.

    Purpose of the Study:

    • To identify the predominant fungal species causing mycotic keratitis in a northern climate.
    • To evaluate the efficacy of pimaricin in treating fungal keratitis, including cases resistant to other antifungals.

    Main Methods:

    • Retrospective case series analysis.
    • Identification of fungal pathogens from corneal scrapings.
    • Clinical outcome assessment following pimaricin treatment.

    Main Results:

    • Candida albicans was the most frequent isolate in this northern cohort.
    • Pimaricin demonstrated effectiveness against Candida albicans keratitis.
    • One case of Aspergillus keratitis, previously unresponsive to amphotericin B, resolved with pimaricin.

    Conclusions:

    • Candida albicans is a primary cause of fungal keratitis in northern regions.
    • Pimaricin serves as a viable therapeutic option for mycotic keratitis, including difficult-to-treat cases.

    Related Experiment Videos