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Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

Open Angle Glaucoma: Treatment

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

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Related Experiment Video

Updated: Jun 18, 2026

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

Screening for glaucoma with stereo disc photography.

R O Schultz¹, R L Radius, A J Hartz

¹Department of Ophthalmology, Medical College of Wisconsin, Milwaukee, Wisconsin, U.S.A.

Journal of Glaucoma

|November 19, 2009

Summary

This summary is machine-generated.

Stereo photographs of the optic nerve head aid in glaucoma detection. This method offers high specificity (95%) and sensitivity (75%) for identifying glaucoma patients, proving valuable for early diagnosis.

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Area of Science:

Ophthalmology
Medical Imaging

Background:

Glaucoma is a leading cause of irreversible blindness worldwide.
Early detection and accurate diagnosis are crucial for managing glaucoma and preventing vision loss.

Purpose of the Study:

To evaluate the diagnostic utility of simultaneous stereo photography of the optic nerve head for glaucoma identification.
To compare the accuracy of stereo photography with other diagnostic methods.

Main Methods:

258 patients underwent comprehensive ophthalmological examinations and glaucoma risk assessments (1-5 scale).
Stereo pairs of the optic nerve head were captured using a NIDEK camera for each patient.
Two independent masked observers reclassified glaucoma likelihood based solely on the stereo photographs.

Main Results:

Stereo photograph analysis achieved a maximum sensitivity of 75% and specificity of 95% for glaucoma identification.
The accuracy was determined by comparing photographic assessments with all available clinical data.

Conclusions:

Stereo optic nerve head photography is a viable tool for glaucoma detection.
This imaging technique demonstrates superior accuracy compared to simple tonometry.
The sensitivity of stereo photography is comparable to screening with computerized perimetry.