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Updated: Aug 14, 2026

Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized 129Xe MRI to Evaluate Lung Structure-Function
Published on: April 12, 2024
Assessment of lung function in children by cross-sectional imaging: techniques and clinical applications
Michael Puderbach1, Hans-Ulrich Kauczor
1Department of Radiology (E010), German Cancer Research Centre, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany. m.puderbach@dkfz.de
Insights
New functional imaging techniques using CT and MRI offer advanced insights into paediatric pulmonary diseases. These methods provide valuable data for diagnosis and monitoring, moving beyond traditional morphological assessments.
Area of Science:
- Medical Imaging
- Paediatric Pulmonology
- Functional Imaging
Background:
- Traditional imaging focused on lung morphology in children.
- Advancements in CT and MRI have enabled functional pulmonary imaging.
Purpose of the Study:
- To review novel cross-sectional functional imaging techniques for the lungs.
- To discuss the clinical value and applications of these methods in paediatric pulmonary diseases.
Main Methods:
- Review of current literature on functional pulmonary imaging.
- Discussion of CT and MRI advancements for lung function assessment.
Main Results:
- Functional imaging provides new insights into paediatric lung conditions.
- These techniques complement traditional morphological imaging.
Conclusions:
- Novel functional imaging techniques are valuable for paediatric pulmonary disease diagnosis and follow-up.
- Potential clinical applications are expanding with technological advancements.
Abstract:
Imaging techniques are indispensable for diagnosis and follow-up of paediatric pulmonary diseases. In the past, interest was focused on morphological aspects of pulmonary tissue. With the development of novel CT and MRI techniques, functional pulmonary imaging became available. In this review, the new techniques of cross-sectional functional imaging of the lung are presented and the value of these methods for investigating paediatric pulmonary diseases and their potential clinical applications are discussed.
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