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Updated: Aug 14, 2026

A Melanoma Patient-Derived Xenograft Model
Published on: May 20, 2019
[Malignant melanoma of the penis. Report on one case]
Maria José Donate Moreno1, Rafael Ruiz Mondejar, José Miguel Giménez Bachs
1Servicio de Urología, Complejo Hospitalario y Universitario de Albacete, Albacete, España. donajiu@ono.com
Objectives:
Due to the fact that melanoma of the penis is rare, we perform a bibliographic review about the subject and analyze the diagnostic criteria, clinical stages and therapeutic options.
Methods:
We report one case that was diagnosed and treated in our department.
Results:
85-year-old male who presented with hematuria and a red brownish irregular elevated lesion in the glans penis. Partial penectomy was performed.
Conclusions:
Melanoma of the penis is a rare tumoral entity. It accounts for about 1% of all penile malignant pathologies. It has bad prognosis due to fast metastosic dissemination (regional lymph nodes and other organs) and delayed diagnosis. First choice treatment is partial penectomy with or without bilateral inguinal lymphadenectomy (depending upon degree of tumor invasiveness). In cases with metastasis treatment is palliative with chemotherapy and immunotherapy
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