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Nephrotic Syndrome III : Nursing Management01:24

Nephrotic Syndrome III : Nursing Management

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Nursing management for nephrotic syndrome adapts as the disease progresses, with strategies evolving to address advancing symptoms and complications.Early-Stage Management In the early stages, nursing interventions for nephrotic syndrome resemble those used in managing acute glomerulonephritis, focusing on symptom monitoring, fluid balance, and managing mild to moderate edema.Vital Signs: Regularly monitor blood pressure, pulse, respiratory rate, and temperature to promptly identify...
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Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such...
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Related Experiment Video

Updated: Jan 18, 2026

The Isolation and Characterization of Low- and Normal- Density Neutrophils from Whole Blood
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Severe chronic neutropenia--a case report.

Sunil Bahl1, Thomas Vurgese, Ali Parappil

  • 1Department of Pathology, Al-Jahra Hospital, Jahra, Kuwait. suruchi_kt@hotmail.com

Indian Journal of Pathology & Microbiology
|November 22, 2005
PubMed
Summary

Severe chronic neutropenia (SCN) is a rare, serious condition. This case report highlights SCN

Area of Science:

  • Hematology
  • Rare Diseases
  • Genetics

Background:

  • Severe chronic neutropenia (SCN) is a rare hematologic disorder affecting approximately 650 individuals globally.
  • Untreated SCN presents significant risks for morbidity and mortality.
  • Understanding SCN mechanisms is crucial for patient management.

Observation:

  • A case of SCN is presented with recurrent hospitalizations due to severe neutropenia and high-grade fever.
  • The patient experienced repeated episodes necessitating medical intervention.
  • This clinical presentation underscores the severity of SCN.

Findings:

  • Literature review details SCN mechanisms, including neutrophil elastase gene mutations.
  • Explores the risk of SCN progression to myelodysplasia and acute leukemia.

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  • Highlights the therapeutic role of granulocyte-colony stimulating factor (G-CSF).

    • Implications:

    • Early diagnosis and management of SCN are critical to reduce complications.
    • Genetic factors play a significant role in SCN pathogenesis.
    • G-CSF therapy is a key treatment modality for managing SCN and its sequelae.