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[Pyoderma gangrenosum in dakar: about 14 cases].

M Diallo1, A Kane, Nt Sy

  • 1Service de Dermatologie, Hôpital Aristide Le Dantec, Dakar-Sénégal.

Dakar Medical
|November 22, 2005
PubMed
Summary

Pyoderma gangrenosum (P.G.) is a rare skin condition. This study highlights its epidemiological, clinical, and evolutionary profiles, noting a high frequency of pediatric cases and effective treatment with oral corticosteroids.

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West African journal of medicine·2024

Area of Science:

  • Dermatology
  • Clinical Medicine
  • Epidemiology

Background:

  • Pyoderma gangrenosum (P.G.) is a rare, ulcerative neutrophilic dermatosis.
  • Understanding its epidemiology and clinical presentation is crucial for diagnosis and management.

Purpose of the Study:

  • To assess the epidemiologic, clinical, and evolutionary profiles of pyoderma gangrenosum.
  • To evaluate treatment outcomes and identify associated pathologies.

Main Methods:

  • Retrospective study of 14 patients diagnosed with P.G. between January 1990 and December 2001.
  • Diagnosis based on clinical and histological findings.
  • Review of patient files for demographic, clinical, and treatment data.

Main Results:

  • The study included 8 males and 6 females with a median age of 24.5 years.
  • Pediatric forms constituted 30% of cases, a notable finding.
  • Lower limb localization (85.7%) and association with chronic ulcerative colitis, rheumatoid spondylitis, and rheumatoid arthritis were observed.
  • Complete cicatrization was achieved in all cases after 11 weeks of oral corticotherapy (1 mg/kg/day), with five recurrences.

Conclusions:

  • Pyoderma gangrenosum is a rare condition with comparable clinical and evolutionary aspects across different series.
  • The high frequency of pediatric cases in this study is remarkable.
  • Oral corticotherapy is an effective treatment for P.G., although recurrences can occur.

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