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Hemophilic pseudotumor.

T R Lewis1, Heather R Webb, Jayson P Bell

  • 1Department of Radiological Sciences, OU College of Medicine, OK, USA.

The Journal of the Oklahoma State Medical Association
|November 22, 2005
PubMed
Summary
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Hemophilic pseudotumors, rare in severe hemophilia, cause bone and soft tissue complications. This case highlights a metacarpal lesion and knee arthropathy in a child with hemophilia.

Area of Science:

  • Orthopedics
  • Hematology
  • Radiology

Background:

  • Bleeding diatheses are characteristic of hemophilia.
  • Hemophilic pseudotumors are rare (1-2% of severe cases), arising from recurrent hemorrhages into bone or soft tissues.
  • Complications include pain, compression of structures, and pathologic fractures due to bone resorption.

Observation:

  • Radiographs revealed an expansile bone lesion in a metacarpal and soft tissue density.
  • Intra-articular bleeding led to joint space hemorrhage.
  • The patient presented with both osseous and intra-articular manifestations.

Findings:

  • The case report details an 11-year-old with severe hemophilia.
  • Demonstrated an expansile lesion of a metacarpal, indicative of a hemophilic pseudotumor.

Related Experiment Videos

  • Showcased associated hemophilic knee arthropathy resulting from intra-articular bleeding.

    • Implications:

    • Highlights the diverse skeletal manifestations of hemophilia.
    • Emphasizes the importance of early diagnosis and management of hemophilic pseudotumors and arthropathy.
    • Underscores the need for vigilance in identifying rare complications in severe hemophilia cases.