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Visual field progression in glaucoma: total versus pattern deviation analyses.

Paul H Artes1, Marcelo T Nicolela, Raymond P LeBlanc

  • 1Department of Ophthalmology and Visual Sciences, Dalhousie University, Halifax, Nova Scotia, Canada. paul_h_artes@yahoo.co.uk

Investigative Ophthalmology & Visual Science
|November 24, 2005
PubMed
Summary
This summary is machine-generated.

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Pattern deviation analysis may underestimate glaucoma progression. Total deviation analysis is often more sensitive for detecting visual field changes, especially diffuse loss. Both methods are crucial for informed clinical decisions.

Area of Science:

  • Ophthalmology
  • Neuroscience
  • Medical Imaging

Background:

  • Glaucoma is a progressive optic neuropathy.
  • Visual field loss is a key indicator of glaucoma progression.
  • Accurate assessment of visual field progression is vital for timely intervention.

Purpose of the Study:

  • To compare the efficacy of total deviation and pattern deviation analyses in detecting visual field progression in glaucoma patients.
  • To evaluate the sensitivity and timing of progression detection between the two analysis methods.

Main Methods:

  • A prospective longitudinal study involving 101 glaucoma patients and 102 healthy controls.
  • Static automated perimetry conducted at 6-month intervals over a median of 9 years.
  • Event and trend analyses applied to both total and pattern deviation values to define progression.

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Main Results:

  • Pattern deviation analysis identified approximately 15% fewer progressing eyes compared to total deviation analysis.
  • Total deviation analysis tended to detect progression earlier than pattern deviation analysis.
  • Glaucomatous visual field changes often include a diffuse component, which pattern deviation may underestimate.

Conclusions:

  • Pattern deviation analysis may underestimate visual field progression in glaucoma, particularly in cases without media opacity changes.
  • Clinicians should utilize both total and pattern deviation analyses for comprehensive assessment and decision-making in glaucoma management.