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[Hürthle-cell tumors of the thyroid]
B Massidda1, A Nicolosi, E Mura
1Istituto di Chirurgia ed Oncologia, Università degli Studi di Cagliari.
Minerva Chirurgica
|May 31, 1992
Summary
Hürthle cell tumors, a rare thyroid neoplasm, showed favorable outcomes in a 10-year study. Surgical management led to disease-free survival for all observed patients, highlighting effective treatment strategies for these thyroid tumors.
Area of Science:
- Endocrinology
- Surgical Oncology
- Pathology
Context:
- Hürthle cell tumors are rare thyroid neoplasms.
- Observed 20 patients over 10 years at the Institute of Surgery and Oncology of Cagliari University.
- Included 17 females and 3 males with a median age of 42 years.
Purpose:
- To analyze the clinical characteristics, surgical management, and outcomes of Hürthle cell tumors.
- To evaluate the efficacy of surgical interventions for both malignant and benign Hürthle cell tumors.
- To assess recurrence rates and long-term survival in patients with Hürthle cell tumors.
Summary:
- Seven of 20 patients had malignant Hürthle cell tumors, while 13 had benign adenomas.
- Total thyroidectomy was performed for carcinomas; less extensive surgery was used for adenomas.
- Malignant cases with metastases were treated with surgery and radioiodine therapy, resulting in disease-free survival.
- Benign adenomas showed no recurrence at a median follow-up of 47 months.
Impact:
- Demonstrates successful surgical management and favorable prognosis for Hürthle cell tumors.
- Highlights the importance of individualized surgical approaches based on tumor type (benign vs. malignant).
- Suggests a need for extended follow-up to definitively confirm the benign nature of adenomas.