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Use of an Integrated Low-Flow Anesthetic Vaporizer, Ventilator, and Physiological Monitoring System for Rodents
Published on: July 9, 2020
[What are the changes in paediatric anaesthesia practice afforded by new anaesthetic ventilators?]
1Département d'anesthésie-réanimation chirurgicale, CHU Dupuytren, 2, avenue Martin-Luther-King, 87042 Limoges, France.
Insights
Modern anesthesia ventilators offer precise volume and pressure control for pediatric patients, adapting to unique respiratory needs and improving gas delivery during anesthesia.
Area of Science:
- Anesthesiology and Respiratory Care
- Pediatric Mechanical Ventilation
Context:
- Pediatric patients have distinct respiratory physiology, including decreased lung compliance and increased oxygen demand.
- Anesthesia machines require specialized ventilators capable of delivering small tidal volumes at high rates with minimal compression loss.
Purpose:
- To review the advancements in anesthesia ventilators crucial for pediatric anesthesia.
- To discuss the benefits and limitations of various ventilation modes in pediatric patients.
Summary:
- Modern anesthesia ventilators compensate for circuit compression, ensuring accurate tidal volume delivery in volume-controlled ventilation.
- Newer modes like pressure-controlled ventilation with 'autoflow' and pressure assist offer improved gas distribution and potential for spontaneous breathing.
- Precise fresh gas flow adjustments are possible due to improved flowmeters and circuit airtightness.
Impact:
- Enhanced ventilator technology improves the safety and efficacy of mechanical ventilation during pediatric anesthesia.
- Understanding these advancements aids clinicians in selecting appropriate ventilation strategies for diverse pediatric cases.
- Further research is needed to clarify the use of pressure assist ventilation in very low-weight infants.
Abstract:
Because of specific paediatric respiratory physiology (mainly decreased compliance and functional residual capacity, increased O2 demand and CO2 production), ventilators for paediatric anaesthesia need to be powerful and able to deliver small volumes at a high rate without compression volume loss. The compensation of compliance now available on every anaesthesia machine, compensates for the volume of gas lost by compression in the circuit tubing allowing the tidal volume to reach preset commands, even for bellow in box respirators. Preset tidal volume is then totally delivered to the lung by volume-controlled ventilation because it becomes independent of total pulmonary compliance and fresh gas flow. Increased precision of electronic flowmeters and better air-tightness of circuits allow reducing with precision fresh gas flow to values approaching children's O2 consumption and N2O diffusion. New modes of ventilation are now available on anaesthesia machine. Pressure controlled mode, by increasing and maintaining mean airway pressures, ameliorates intrapulmonary gas distribution and compensates for the gas leak from uncuffed tracheal tubes. Unsteady tidal volume resulting from variation of total compliance, is the main drawback of pressure-controlled ventilation that may be overcome by using the "autoflow" mode (better described as a pressure controlled mode ensuring tidal volume) available with one of the last generation of ventilators. Increased accuracy and security of the mode "pressure assist" might increase the use of spontaneous ventilation in paediatric anaesthesia even for low weight children. However tidal volume remains variable with compliance and depth of anaesthesia, which may require several adjustments of ventilator's settings. The clinical conditions (mainly airway control) of pressure assist use for children less than 10 kg should be elucidated before recommending its use.
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