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[Present status and research train of thoughts in integrative medicine on unstable plaque]

Jing-chun Zhang1, Ke-ji Chen, Wen-gao Ahang

  • 1Xiyuan Hospital, China Academy of Traditional Chines Medicine, Beijing 100091. zhangjingchun276@sohu.com

Zhongguo Zhong Xi Yi Jie He Za Zhi Zhongguo Zhongxiyi Jiehe Zazhi = Chinese Journal of Integrated Traditional and Western Medicine
|November 30, 2005
PubMed

Insights

Stabilizing unstable atherosclerosis (AS) plaque is crucial for preventing cardiovascular events. Traditional Chinese Medicine (TCM) offers a promising approach by addressing inflammation and plaque instability.

Area of Science:

  • Cardiovascular Medicine
  • Pharmacology
  • Integrative Medicine

Context:

  • Atherosclerosis (AS) plaque instability is a key factor in cardio-cerebrovascular events.
  • Inflammation significantly contributes to AS plaque formation and rupture.
  • Current research focuses on stabilizing AS plaque to prevent adverse outcomes.

Purpose:

  • To review recent studies on stabilizing unstable AS plaque using integrated Chinese and Western medicine.
  • To introduce the theory of "unstable plaque induced by toxin and stagnation" in Traditional Chinese Medicine (TCM).
  • To explore TCM interventions for unstable plaque by removing toxins and activating blood flow.

Summary:

  • Atherosclerosis plaque progression and instability are linked to cardiovascular events.
  • Traditional Chinese Medicine (TCM) demonstrates potential in stabilizing AS plaque due to its multi-target and milder adverse effect profile.
  • This review examines integrated Chinese and Western medicine approaches, proposing a TCM-based theory and intervention strategy for unstable plaque.

Impact:

  • Provides a theoretical framework and potential therapeutic strategies for stabilizing AS plaque using TCM.
  • Offers an objective experimental and clinical basis for TCM's role in preventing cardio-cerebrovascular diseases.
  • Highlights the advantages of TCM in managing complex diseases like atherosclerosis with fewer side effects.

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