Related Experiment Video
Updated: Aug 14, 2026

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
Published on: May 26, 2023
Effects of three groin compression methods on patient discomfort, distress, and vascular complications following a
Linda L Chlan1, Julie Sabo, Kay Savik
1School of Nursing, University of Minnesota, 5-160 Weaver-Densford Hall, 308 Harvard Street SE, Minneapolis, MN 55455, USA. chlan001@umn.edu
Insights
Vascular complication rates after percutaneous coronary intervention (PCI) procedures did not differ significantly between Femostop, C-clamp, and manual compression methods. Vigilance is needed for patients with pre-existing vascular complications or those on antiplatelet medications.
Area of Science:
- Cardiology
- Interventional Cardiology
- Vascular Surgery
Background:
- Vascular complications (VCs) following percutaneous coronary intervention procedures (PCIPs) vary based on the hemostasis method used.
- Effective hemostasis is crucial for minimizing post-procedural complications.
Purpose of the Study:
- To compare the efficacy of Femostop, C-clamp, and manual compression in reducing patient discomfort and vascular complications after PCIP.
- To identify the optimal compression method for femoral artery hemostasis.
Main Methods:
- A three-group experimental study involving 306 patients undergoing PCIPs.
- Random assignment to Femostop, C-clamp, or manual compression groups.
- Assessment of patient-reported discomfort and VCs at multiple time points.
Main Results:
- No significant differences in discomfort, distress, or VCs were observed among the three compression methods.
- Pre-existing VCs before sheath removal were associated with increased oozing, hematoma, and ecchymosis.
- Specific compression methods showed minor benefits based on hemostasis duration, and eptifibatide use influenced ecchymosis rates.
Conclusions:
- Nurses should monitor patients with pre-existing VCs or those on antiplatelet medications closely.
- Further research is required to identify patient-specific factors contributing to VCs after PCIP.
Background:
Incidence of vascular complications (VCs) after sheath removal following a percutaneous coronary intervention procedure (PCIP) vary widely by the compression method used to achieve femoral artery hemostasis.
Objective:
To determine if one groin compression method causes the least discomfort and distress for patients and results in fewer VCs.
Methods:
Patients (n = 306, mean age = 62.3 years, 77% male, 96.4% Caucasian) undergoing PCIPs at a tertiary care center in the urban Midwest participated in this three-group experimental design study. They were randomly assigned to Femostop, C-clamp, or manual compression and rated level of groin discomfort and distress on a 0-10 Numeric Rating Scale (NRS) prior to, during, and after arterial compression was released. The groin area was assessed for any VCs (oozing, ecchymosis, hematoma) prior to sheath removal, after compression released, and 12 and 24 hr after sheath removal.
Results:
No significant differences were found by compression method for discomfort, distress, or VCs. Regardless of method, not having a VC prior to femoral sheath removal contributes to less oozing (z = -3.1, p = .0019), hematoma (z = -9.4, p < .0001), and ecchymosis(z = -10.1, p < .0001). C-clamp contributes to less oozing when hemostasis time is < 30 min (z = -2.2, p = .03), and Femostop is superior when time to hemostasis is >30 min (z = -2.3, p = .02). Not receiving eptifibatide (Integrilin) contributes to less ecchymosis (z = -2.9, p = .004).
Conclusions:
Nurses need to be vigilant when caring for patients who have a VC prior to femoral sheath removal and have received antiplatelet medications. Further research is needed to identify patient characteristics that may contribute to VCs.
Related Concept Videos
Peripheral Artery Disease V: Postoperative Nursing Management
Peripheral Artery Disease III: Interprofessional Care
Cardiac Catheterization I: Pre-Procedure Overview
Cardiac Catheterization IV: Nursing Management
Peripheral Artery Disease IV: Nursing Management
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
