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Inhibition of neutrophil elastase and thrombin activity by caffeic acid esters

M F Melzig1, G D Tran, K Henke

  • 1Institute of Pharmacy, Free University Berlin, Königin-Luise-Str. 2 + 4, D-14195 Berlin, Germany. melzig@zedat.fu-berlin.de

Die Pharmazie
|December 3, 2005
PubMed
Summary

Caffeic acid esters effectively inhibit neutrophil elastase, an enzyme involved in inflammation. The lipophilic nature and chain structure of these esters enhance inhibition, suggesting potential therapeutic applications for inflammatory diseases.

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