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Updated: Aug 14, 2026

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Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
Published on: November 20, 2015
[Perinatal pathology in HIV-infection]
Arkhiv Patologii
|December 6, 2005
Summary
This study details structural changes in placentas and fetuses due to human immunodeficiency virus (HIV) infection. It describes characteristic cellular alterations and discusses perinatal transmission routes and intrauterine infection pathogenesis.
Area of Science:
- Pathology
- Virology
- Obstetrics
Context:
- Analysis of existing literature and original data on HIV-related structural changes.
- Focus on placental, fetal, and neonatal tissues.
- Examination of histopathological alterations.
Purpose:
- To describe characteristic cellular changes in HIV infection.
- To elucidate the pathogenesis of intrauterine and perinatal HIV transmission.
- To correlate structural abnormalities with HIV infection.
Summary:
- Presents findings on structural alterations in placenta, fetuses, and deceased children.
- Details specific HIV-associated cellular changes, including cell enlargement and nuclear size variations.
- Discusses mechanisms of perinatal infection and intrauterine transmission pathways.
Impact:
- Enhances understanding of HIV's impact on fetal development.
- Provides insights into the pathological mechanisms of vertical HIV transmission.
- Contributes to the knowledge base for managing HIV in pregnancy and preventing infant infection.
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