Related Experiment Video
Updated: Aug 14, 2026

Microsurgical Creation of Giant Bifurcation Aneurysms in Rabbits for the Evaluation of Endovascular Devices
Published on: September 8, 2023
[A grading scale for endovascular treatment of intracranial aneurysms]
Ming Lü1, Zhong-xue Wu, You-xiang Li
1Department of Interventional Neuroradiology, Neurosurgical Institute, Beijing 100050, China.
Objective:
To investigate the factors influencing the embolizing plan and result of intracranial aneurysms, and to establish a new grading scale for endovascular treatment of intracranial aneurysms.
Methods:
The clinical data of 156 aneurysms in 151 patients, 67 males and 84 females, aged 4-80, were prospectively collected to analyze the influences of sex, age, aneurysmal DSA manifestation (including location, shape, longest diameter, neck width and sac-neck ratio) and whether or not embolizing in acute phase on the therapeutic alternatives and immediate embolizing results.
Results:
Logistic regression analyses showed that aneurysmal location (OR = 3.734, P = 0.018), neck width (OR = 16.279, P = 0.000) and sac-neck ratio (OR = 4.090, P = 0.003) were predictive factors of the therapeutic alternatives, and the longest diameter (OR = 2.725, P = 0.024), neck width (OR = 2.600, P = 0.033) and sac-neck ratio (OR = 3.144, P = 0.003) were predictive factors of the embolizing results. Aneurysmal location (0 for internal carotid system, and 1 for vertebro-basilar system), the longest diameter (0 for < 8 mm, and 1 for > or = 8 mm), neck width (0 for < 4 mm, and 1 for > or = 4 mm or without neck) and sac-neck ratio (0 for > 1.2, and 1 for < or = 1.2 or without neck) were regarded as grading items to establish the intracranial aneurysm endovascular scale (IAES), which ranked the intracranial aneurysms into four grades. The zero and first grades were ordinary aneurysms, and the second to fourth grades were complicated aneurysms.
Conclusion:
IAES helps the clinicians to determine the individualized embolizing plan and predict the embolizing effect.
Related Concept Videos
Aneurysm III: Interprofessional Care
Aneurysm IV: Nursing Management
Aneurysm II: Clinical Manifestations and Diagnostic Studies
Aneurysm I: Introduction

