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[Radioguided occult breast lesion location (ROLL)]
M Cortés Romera1, R Pardo García, A Soriano Castrejón
1Servicio de Medicina Nuclear, Complejo Hospitalario de Ciudad Real, Ciudad Real. mcortesr@sescam.jccm.es
Revista Espanola De Medicina Nuclear
|December 6, 2005
Summary
Radioguided occult breast lesion localization using radiopharmaceuticals is a safe and effective method for precisely locating non-palpable breast abnormalities. This technique ensures accurate surgical removal of suspicious lesions, aiding in timely diagnosis and treatment.
Area of Science:
- Nuclear medicine
- Radiopharmacology
- Breast imaging
Background:
- Accurate localization of occult breast lesions is crucial for effective diagnosis and treatment.
- Non-palpable lesions detected mammographically pose challenges for surgical excision.
Purpose of the Study:
- To evaluate the efficacy of radiopharmaceutical methods for precise localization of occult breast lesions.
- To assess the safety and patient tolerance of radioguided localization techniques.
Main Methods:
- Sixty-one patients with mammographically detected non-palpable breast lesions underwent localization using technetium-99m-labeled human serum albumin macroaggregates (99mTc-MAA).
- Radiotracer injection was guided by stereotactic mammography or ultrasonography, with scintigraphic verification.
- Intraoperative localization utilized a gammaprobe, and specimen radiography confirmed microcalcification removal.
Main Results:
- Successful radiotracer placement was achieved in 95.2% (60/63) of cases.
- Sixty-one lesions were completely excised, with pathological examination revealing 47.6% breast cancers and 52.4% benign findings.
- The method demonstrated high accuracy in guiding surgical removal of occult breast lesions.
Conclusions:
- Radioguided occult breast lesion localization using radiopharmaceuticals is a simple, safe, and well-tolerated procedure.
- This technique facilitates accurate and complete excision of non-palpable breast abnormalities.
- It represents a valuable tool in the management of breast cancer diagnosis and treatment.