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Updated: Jul 29, 2026

Atomic Force Microscopy Imaging and Force Spectroscopy of Supported Lipid Bilayers
Published on: July 22, 2015
Supported bilayer lipid membranes modified with a phosphate ionophore
Yan Li Zhang1, James Dunlop, Thai Phung
1AgResearch, Grasslands Research Centre, Tennent Drive, Private Bag 11008, Palmerston North, New Zealand. Yan-Li.zhang@agresearch.co.nz
Abstract:
This article reports the electrical responses of a phosphate ionophore, the cyclic polyamine 3-decyl-1,5,8-triazacyclodecane-2,4-dione (N3-cyclic amine) incorporated into metal supported bilayer lipid membranes (s-BLM). Teflon coated silver wire was used as a support. In a potentiometric mode, the ionophore had a response that was linearly related to the logarithm of HPO4(2-) concentration and was also dependant on pH. Selectivity coefficients for other anions compared to HPO4(2-) ions, determined by the separate solution method, fell within the range 1.73 x 10(-4) to 6.38 x 10(-2).
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