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Related Experiment Videos

Autonomic function and dysfunction of the nose and sinuses.

Todd A Loehrl1

  • 1Division of Rhinology and Sinus Surgery, Department of Otolaryngology, Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, WI 53226, USA. tloehrl@mcw.edu

Otolaryngologic Clinics of North America
|December 6, 2005
PubMed
Summary

Patients with upper airway inflammatory disorders show autonomic nervous system (ANS) dysfunction. Further research is needed to understand the ANS

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Area of Science:

  • Otolaryngology
  • Immunology
  • Neuroscience

Background:

  • Upper airway inflammatory disorders are common.
  • Autonomic nervous system (ANS) dysfunction is observed in these patients.
  • The precise role of ANS dysfunction in sinonasal inflammation is not fully understood.

Purpose of the Study:

  • To investigate the relationship between autonomic nervous system dysfunction and sinonasal inflammation.
  • To explore the interaction between the ANS and inflammatory processes in the upper airway.

Main Methods:

  • This study reviews current evidence on ANS function in patients with upper airway inflammatory disorders.
  • Analysis of sympathetic, parasympathetic, and sensory components of the ANS.

Main Results:

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  • Patients with upper airway inflammatory disorders present with varied degrees of ANS dysfunction.
  • Evidence is currently insufficient to establish a definitive role for ANS dysfunction in these conditions.

Conclusions:

  • The interaction between the autonomic nervous system and sinonasal inflammation warrants further investigation.
  • Understanding this relationship may lead to novel therapeutic strategies for upper airway inflammatory disorders.