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Squamous cell carcinoma arising from a fibroepithelial polyp
Hakan Agir1, Cenk Sen, Deniz Cek
1Kocaeli University Medical Faculty, Department of Plastic, Aesthetic, and Reconstructive Surgery, Kocaeli, Turkey. adirhakan@yahoo.com
Annals of Plastic Surgery
|December 6, 2005
Summary
Fibroepithelial polyps (FEPs) are common benign skin lesions. This case report details a rare instance of aggressive squamous cell carcinoma developing from a large FEP on the lower limb.
Area of Science:
- Dermatology
- Oncology
- Pathology
Background:
- Fibroepithelial polyps (FEPs) are common benign skin neoplasms.
- Malignant transformation of FEPs is exceptionally rare, leading to infrequent histologic examination.
- This rarity contributes to a potential underestimation of associated risks.
Observation:
- A case report of a patient presenting with a large, pedunculated-type FEP on the lower limb.
- The FEP exhibited an unusual and aggressive gross squamous cell carcinoma (SCC) mass.
- The lesion's location on the lower limb is noteworthy for this type of presentation.
Findings:
- Histologic examination confirmed the presence of squamous cell carcinoma arising from the FEP.
- The aggressive nature of the SCC mass was evident on gross examination.
- This represents a unique and previously unreported association between FEPs and aggressive SCC.
Implications:
- Highlights the importance of considering malignant potential even in typically benign lesions like FEPs.
- Suggests that thorough histologic examination may be warranted for large or atypical FEPs.
- Underscores the need for vigilance in dermatologic and oncologic practice regarding rare but aggressive presentations.