Related Experiment Video
Updated: Aug 14, 2026
Correction of Presbyopia by Monocular Bi-Aspheric Ablation Profile
Published on: September 20, 2024
Conventional vs wavefront-guided LASIK using the LADARVision4000 excimer laser
Andrew I Caster1, James L Hoff, Roman Ruiz
1Caster Eye Center, Beverly Hills, CA, USA. acaster@castervision.com
Purpose:
To compare outcomes after LASIK surgery using the conventional LADARVision4000 laser and the wavefront-guided LADARWave CustomCornea wavefront system.
Methods:
A prospective study was performed involving 140 myopic eyes receiving conventional or CustomCornea LASIK between May and October 2003. The preoperative manifest spherical equivalent refraction was limited to myopia < or = -7.00 diopters (D). The preoperative manifest cylinder was limited to < or = -2.50 D of astigmatism. Patients were evaluated for 3 months following surgery. Results evaluated were uncorrected visual acuity (UCVA), best spectacle-corrected visual acuity, manifest refraction, dilated wavefront measurements, contrast sensitivity, and patient responses to subjective questionnaires.
Results:
For the CustomCornea eyes at 3 months, 80% (70/87) had UCVA > or = 20/20 and 95% (83/87) had UCVA > or = 20/25. For the conventional eyes at 3 months, 45% (9/20) had UCVA > or = 20/20 and 80% (16/20) had UCVA > or = 20/25. At the 3-month postoperative visit, 85% (74/87) of the CustomCornea eyes and 55% (11/20) of the conventional eyes were within +/- 0.50 D of their intended correction. At 1 and 3 months, the CustomCornea treated eyes had a statistically significant lower mean increase in higher order aberrations than conventionally treated eyes (P < .05).
Conclusions:
CustomCornea wavefront-guided LASIK surgery appears safe and effective and provides clinical benefits that appear to exceed those of conventional LADARVision surgery.
