Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Towards an inline reconstruction architecture for micro-CT systems.

David Brasse1, Bernard Humbert, Carole Mathelin

  • 1Institut de Recherches Subatomiques, IN2P3-CNRS/ULP, Strasbourg, France. david.brasse@ires.in2p3.fr

Physics in Medicine and Biology
|December 8, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evolution of germline testing, mutation spectrum and clinico-pathological features in male breast cancer: a 27-year retrospective cohort including 69 patients.

Cancer genetics·2026
Same author

Survey of the Senologic International Society (SIS) on the Use of Preoperative Breast MRI in Early-Stage Breast Cancer: A Global Perspective on Current Practice.

European journal of breast health·2026
Same author

Contralateral Risk Reduction Mastectomy in Patients With Unilateral Breast Cancer Scheduled for Mastectomy: A Multidisciplinary Survey; Physicians' Perspective.

Clinical breast cancer·2026
Same author

[(Even) less axillary surgery for breast cancer?]

Gynecologie, obstetrique, fertilite & senologie·2026
Same author

Assessing Lead Exposure by Biological Matrices Analysis and Links to Breast Cancer: A Critical Review of Experimental and Epidemiological Findings.

European journal of breast health·2025
Same author

Validation of a FLASH-ready 25 MeV proton beamline for preclinical radiobiology experiments.

Physics in medicine and biology·2025

This study introduces a novel inline micro-computed tomography (micro-CT) system for real-time 3D imaging of live animal models. The system achieves high spatial resolution with low radiation dose and rapid acquisition/reconstruction times for efficient biological research.

Area of Science:

  • Medical Imaging
  • Biomedical Engineering
  • X-ray Imaging

Background:

  • Micro-computed tomography (micro-CT) is crucial for in vivo imaging of experimental animal models.
  • Key requirements for biological researchers include high spatial resolution, low radiation dose, and fast acquisition/reconstruction times.

Purpose of the Study:

  • To develop an inline acquisition and reconstruction architecture for real-time 3D attenuation map generation in micro-CT.
  • To meet the critical needs of biological researchers for efficient in vivo imaging.

Main Methods:

  • The micro-CT system utilizes a commercially available X-ray detector and micro-focus X-ray source.
  • An inline architecture with a PC cluster implements a combined serial and parallel processing scheme.
  • A dedicated data acquisition system enhances data transmission rates.

Related Experiment Videos

Main Results:

  • The system achieves real-time 3D attenuation map generation.
  • Reconstruction time for a 140-megavoxels volume using the Feldkamp algorithm is approximately 500 ms.
  • Acquisition time for a single projection matches the reconstruction time, enabling rapid screening.

Conclusions:

  • The developed inline micro-CT architecture successfully fulfills the requirements for in vivo animal imaging.
  • This technology significantly reduces imaging time, enabling high-throughput screening of experimental models.
  • The system offers a powerful tool for advancing biological research through efficient 3D imaging.