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Contralateral Risk Reduction Mastectomy in Patients With Unilateral Breast Cancer Scheduled for Mastectomy: A
Nina M Verghis1, Kazim Senol2, Shigeru Imoto3
1Breast Surgery Unit, Department of Surgical Oncology, UPMC Magee-Womens Hospital, Pittsburgh, PA.
Clinical Breast Cancer
|February 13, 2026
Summary
Contralateral risk reduction mastectomies (RRM) are increasing, but expert consensus on patient selection is lacking. This survey reveals varied practices among breast specialists worldwide, indicating a need for standardized guidelines.
Area of Science:
- Oncology
- Surgical Oncology
- Breast Surgery
Background:
- The incidence of contralateral risk reduction mastectomies (RRM) is rising globally.
- Existing guidelines for RRM patient selection lack universal consensus.
- This study addresses the need to understand current RRM practices and expert opinions.
Purpose of the Study:
- To evaluate the current practices, perspectives, and attitudes of breast specialists regarding contralateral risk reduction mastectomies (RRM).
- To identify variations in RRM decision-making across different medical specialties and geographical regions.
Main Methods:
- An electronic survey with ten questions was developed and distributed to members of the Senologic International Society (SIS).
- The survey focused on assessing current approaches and viewpoints concerning RRM.
Main Results:
- The survey highlights significant diversity in RRM practices and opinions among breast specialists worldwide.
- Variations were observed across different specialties and international locations.
- The findings underscore a lack of uniform recommendations for RRM.
Conclusions:
- There is a clear need for the development of uniform recommendations and guidelines for contralateral risk reduction mastectomies (RRM).
- Further research is essential to improve patient outcomes and standardize the management of RRM.
- Addressing these variations can enhance the care of patients undergoing RRM.
