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Updated: Aug 14, 2026
Robotic Duodenal Sleeve Resection for Gastrointestinal Stromal Tumor with Rare Exon 8 KIT Mutation Following Neoadjuvant Imatinib
Published on: April 3, 2026
[Klinefelter's syndrome diagnosed three years after surgery for mediastinal teratoma]
J Margery1, J P Le Berre, C Bredin
1Service de pneumologie, HIA Percy, Clamart (92). j.margery@wanadoo.fr
Introduction:
The association between some types of tumor and Klinefelter's syndrome (KS) is often missed and diagnosis of the latter delayed, as in this case report.
Case:
We present the case of a 20 year-old patient for whom KS was not diagnosed until three years after thoracic surgery for a mediastinal teratoma.
Discussion:
The association between KS and mediastinal germ-cell tumors is not coincidental; it illustrates the relation between aneuploidy and oncogenesis. In a young adult male, palpation of the scrotum to look for microorchidism is justified when these tumors are diagnosed because 25% occur in patients with KS.
