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Does the interval between prostate biopsy and radical prostatectomy affect the immediate postoperative outcome?
Daniel K Lee1, Veerasuthpursh Allareddy, Michael A O'donnell
1Department of Urology, University of Iowa, Iowa City, IA, USA.
BJU International
|December 13, 2005
Summary
The time between prostate biopsy and radical prostatectomy (RP) surgery does not impact immediate postoperative outcomes. This study found no significant differences in complications or recovery metrics based on the biopsy-to-RP interval.
Area of Science:
- Urology
- Surgical Oncology
Background:
- Prostate biopsy is a standard diagnostic procedure.
- Radical prostatectomy (RP) is a common treatment for prostate cancer.
Purpose of the Study:
- To investigate the impact of the time interval between prostate biopsy and radical prostatectomy (RP) on immediate postoperative outcomes.
Main Methods:
- Retrospective chart review of 169 patients undergoing retropubic RP.
- Univariate and multivariate logistic regression analyses were used.
- Evaluated predictors of operative duration, blood loss, complications, and continence.
Main Results:
- No significant differences in operative duration, blood loss, nerve-sparing rates, transfusion rates, hospitalization, positive margin rates, complications, or continence were observed.
- The biopsy-to-RP interval was not an independent predictor of any postoperative outcomes.
- No correlations were found between the biopsy-to-RP interval and outcomes.
Conclusions:
- The interval between prostate biopsy and retropubic RP does not appear to affect immediate postoperative outcomes.
- A specific minimum interval beyond two weeks before RP cannot be determined from this study.