Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Contrast material-induced renal failure: an overview.

Rainer Schräder¹

¹Cardiology Department, Frankfurt, Germany. r.schraeder@ccb.de

Journal of Interventional Cardiology

|December 13, 2005

Summary

Contrast-induced nephropathy (CIN) is a risk with iodinated contrast media (CM) in cardiovascular procedures. This review covers CIN pathogenesis, prevention strategies, and management for at-risk patients, particularly those with pre-existing conditions.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Carboxylic acid mediated antimicrobial activity of silicone elastomers.

Materials science & engineering. C, Materials for biological applications·2020

Same author

Small Molecule Subgraph Detector (SMSD) toolkit.

Journal of cheminformatics·2010

Same author

Thrombosis, fracture, and percutaneous removal of a patent foramen ovale closure device 1 month after successful deployment.

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions·2010

Same author

Recurrent events following patent foramen ovale closure in patients above 55 years of age with presumed paradoxical embolism.

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions·2008

Same author

Incidence of atrial fibrillation following transcatheter closure of atrial septal defects in adults.

The American journal of cardiology·2008

Same author

Comparison of contemporary devices used for transcatheter patent foramen ovale closure.

The Journal of invasive cardiology·2008

Area of Science:

Cardiology
Nephrology
Radiology

Background:

Iodinated contrast media (CM) are essential for cardiovascular procedures, offering diagnostic benefits.
A small percentage of patients experience adverse events, with contrast-induced nephropathy (CIN) being the most serious complication.
Patients with renal insufficiency, diabetes mellitus, or cardiovascular disease undergoing intra-arterial contrast administration are at higher risk for CIN.

Purpose of the Study:

To review the pathogenesis of contrast-induced nephropathy (CIN).
To discuss current strategies for preventing CIN.
To outline the management of patients at risk for CIN.

Main Methods:

Review of existing literature on contrast-induced nephropathy.
Analysis of risk factors and patient populations susceptible to CIN.
Synthesis of current clinical opinions on CIN prevention and management.

Main Results:

CIN typically manifests as changes in serum creatinine 1-5 days post-contrast.
While often transient, CIN can lead to prolonged renal dysfunction and, rarely, dialysis.
Patients with CIN experience increased morbidity, including prolonged hospitalization and higher mortality rates.

Conclusions:

Understanding CIN pathogenesis is crucial for effective prevention.
Proactive management and risk stratification are essential for patients undergoing contrast-enhanced procedures.
Minimizing CIN risk is vital for improving patient outcomes and reducing healthcare burdens.

Related Experiment Videos