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Updated: Jul 30, 2026

Isolation and Quantification of Epstein-Barr Virus from the P3HR1 Cell Line
Published on: September 28, 2022
Absence of Epstein-Barr virus in esophageal squamous cell carcinoma
S Sunpaweravong1, W Mitarnun, P Puttawibul
1Department of Surgery, Songklanagarind Hospital, Prince of Songkla University, Songkla, Thailand. susomkia@medicine.psu.ac.th
Abstract:
It is strongly suspected that the Epstein-Barr virus (EBV) plays a role in the genesis of nasopharyngeal and gastric carcinoma. The aim of this study was to search for such a connection between esophageal squamous cell carcinoma (ESCC) and EBV. We investigated 104 surgically resected esophageal cancers using in situ hybridization (ISH) for EBV-encoded RNA (EBER). We found no EBER-positive cancer cells in any tests, although there were five samples in which EBER-positive tumor-infiltrating lymphocytes (TILs) were found. We conclude from this study that EBV is not associated with ESCC.
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