Related Experiment Video
Updated: Sep 3, 2026

Three-Dimensional Cell Culture Models to Investigate the Epithelial Barrier in Eosinophilic Esophagitis
Published on: May 10, 2024
[Eosinophilic esophagitis: update 2026]
Amaëlle Denys1, Alain Schoepfer1
1Service de gastroentérologie et d'hépatologie, Centre hospitalier universitaire vaudois et Université de Lausanne, 1011 Lausanne.
Abstract:
Eosinophilic esophagitis (EoE) is a chronic inflammatory disease characterized by esophageal dysfunction symptoms (dysphagia, retrosternal pain, food impaction), typical endoscopic changes, and eosinophilic infiltration of the mucosa. Since the first description of this condition more than 30 years ago, the number of diagnosed patients has significantly increased. The role of the environment in this increase and the pathogenesis are becoming increasingly well understood, although many questions remain unanswered. This article discusses the latest advances in EoE research and the currently available therapeutic options.
Related Concept Videos
Barrett Esophagus-II: Clinical Manifestations and Management
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure entails...
Gastroesophageal Reflux Disease II: Clinical Features and Management
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
Esophageal Strictures-II: Clinical Features and Management
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
Barrett Esophagus-I: Introduction
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more similar...
Esophageal Strictures-I: Introduction
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
Gastroesophageal Reflux Disease
