Related Experiment Video
Updated: Feb 7, 2026
07:44
Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction
Published on: March 25, 2022
6.8K
EUS-guided pancreatic duct drainage: a single-center observational study
Elodie Romailler1, Anouk Voutaz2, Sarra Oumrani1
1Department of Gastroenterology and Hepatology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.
Igie : Innovation, Investigation and Insights
|February 6, 2026
Summary
Endoscopic retrograde cholangiopancreatography (ERCP) can fail for pancreatic duct obstruction. Endoscopic ultrasound (EUS)-guided pancreatic duct drainage offers a successful, minimally invasive alternative for patients needing treatment.
Area of Science:
- Gastroenterology
- Interventional Endoscopy
- Surgical Oncology
Background:
- Pancreatic duct obstruction causes pain and pancreatic atrophy.
- Endoscopic retrograde cholangiopancreatography (ERCP) is the standard treatment.
- Transpapillary ERCP may fail due to anatomical challenges or ductal abnormalities.
Purpose of the Study:
- To evaluate the clinical success of EUS-guided pancreatic duct drainage.
- To assess EUS-guided drainage as an alternative to surgery for complex cases.
- To determine the efficacy in patients with failed ERCP.
Main Methods:
- Retrospective review of 46 patients undergoing EUS-guided pancreatic duct drainage (2016-2022).
- Clinical success defined by pain reduction (VAS ≤2) and absence of recurrent pancreatitis.
- Weight stabilization or regain used for chronic pancreatitis with weight loss.
Main Results:
- Technical success achieved in 93.5% of patients.
- Clinical success rate was 93% among those with technical success.
- Low rates of pain recurrence (9.3%) and pancreatitis recurrence (6.9%) observed.
Conclusions:
- EUS-guided pancreatic duct drainage is a highly successful minimally invasive procedure.
- It provides an effective alternative for patients with symptomatic pancreatic duct stenosis who failed ERCP.
- This technique can help avoid pancreatic surgery for benign or malignant etiologies.
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