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Updated: Aug 14, 2026
Enhancement of Facial Rejuvenation Through a Combination of 1565 nm Non-Ablative Fractional Laser with 30% Supramolecular Salicylic Acid
Published on: September 27, 2024
Nonablative wrinkle treatment of the face and neck using a combined diode laser and radiofrequency technology
Neil S Sadick1, Mario A Trelles
1Department of Dermatology, Weill Medical College of Cornell University, New York, NY, USA. nssderm@sadickdermatology.com
Background:
Nonablative laser systems that integrate optical and conducted radiofrequency (RF) energies are a novel technology for the treatment of wrinkles.
Objective:
This two-center study investigated the safety and effectiveness of combination diode laser (900 nm) and RF for the treatment of wrinkles and skin texture.
Methods:
Patients with grade II to IV wrinkling on the face, according to the Glogau classification system, were treated with a combination diode laser and RF using a fluence of 30 to 50 J/cm2 and RF energy of 80 to 100 J/cm3. Patients received up to three treatment sessions at 2- to 3-week time intervals. Wrinkle assessments using the Glogau scale were conducted at baseline and at 3 months following the last treatment. In addition, patients and physicians graded the level of improvement using pre- and post-treatment photographs.
Results:
Twenty-three subjects completed all three treatment sessions. Of these participants, more than 50% had a greater than 50% improvement in the appearance of wrinkles. All subjects reported a noticeable improvement in skin smoothness and texture.
Conclusion:
This preliminary study demonstrates that the combination of diode laser and RF energies decreases the appearance of wrinkles and improves skin texture.
