[Evaluation of predisposing factors and bacteriologic agents in pediatric rhinosinusitis]

Hülya Eyigör1, Sema Başak

  • 1Department of Otolaryngology, Aydin State Hospital, Aydin, Turkey. hulinar@yahoo.com

Insights

This study identified common causes of acute rhinosinusitis in children, finding smoking, adenoid obstruction, and anatomical variations as frequent predisposing factors. Streptococcus pneumoniae and Haemophilus influenzae were the most common bacterial agents identified in pediatric patients.

Area of Science:

  • Pediatric Otolaryngology
  • Infectious Diseases

Background:

  • Acute rhinosinusitis (ARS) is a common pediatric condition with various potential predisposing factors.
  • Identifying these factors and causative pathogens is crucial for effective management and treatment strategies.

Purpose of the Study:

  • To investigate the predisposing factors and bacteriologic agents associated with acute rhinosinusitis in a pediatric population.
  • To correlate clinical findings with microbiological and radiological data in children with ARS.

Main Methods:

  • A cohort of 76 children diagnosed with ARS underwent detailed history taking, otolaryngologic examination, nasal endoscopy, allergy testing, and Water's radiography.
  • Middle meatal aspiration cultures were obtained to identify bacterial pathogens.
  • Patients were treated with antibiotics such as ampicillin-sulbactam, loracarbef, or amoxicillin-clavulanate, with a one-year follow-up for recurrence.

Main Results:

  • The most common symptoms included nasal obstruction (92.1%) and rhinorrhea (89.4%).
  • Predisposing factors identified were smoking history (51.3%), septal deviation (21.1%), and choanal obstruction by adenoid tissue (32.9%).
  • Pathology was noted in 93.2% of Water's graphs. Cultures revealed Streptococcus pneumoniae (41.1%) and Haemophilus influenzae (30.4%) as the most prevalent pathogens.

Conclusions:

  • Smoking, adenoid tissue obstruction, anatomical variations, and allergies are significant predisposing factors for ARS in children.
  • Streptococcus pneumoniae and Haemophilus influenzae are the primary bacterial agents responsible for pediatric ARS.
  • While treatment options varied, factors like adenoid size and allergy did not significantly impact treatment success.
Abstract

Related Concept Videos

Microbiota of the Respiratory Tract01:29

Microbiota of the Respiratory Tract

The human respiratory tract, comprising the upper and lower segments, serves as a critical interface with the external environment. The upper respiratory tract (URT)—including the nostrils, sinuses, pharynx, and oropharynx—is heavily colonized by microbes, while the lower respiratory tract (LRT), composed of the larynx, trachea, bronchi, and lungs, was long thought to be sterile. However, recent molecular studies have revealed that the lungs are not devoid of microbes but act more like...
Bacterial Meningitis II: Pathophysiology01:26

Bacterial Meningitis II: Pathophysiology

Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...
Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
Acute Pharyngitis01:30

Acute Pharyngitis

Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
Bacterial Meningitis I: Introduction01:22

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
Tonsillitis I: Introduction01:30

Tonsillitis I: Introduction

Tonsillitis is inflammation of the tonsils, which are two lymphoid tissue masses at the back of the throat. This condition can cause discomfort and irritation in the throat.
Etiology
Three primary contributing factors have been identified.